Cayman Chemical ANTIBODY LY3000328 500ug
A potent cathepsin S inhibitor (IC50 = 7.7 nM for the human enzyme); selective for cathepsin S over cathepsin L, K, B, and V (IC50s = >10,000, >10,000, 4,390, and 21,500 nM, respectively); reduces aortic diameter in a mouse model of calcium chloride-induced abdominal aortic aneurysm from 1-30 mg/kg